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9. Reproductive toxicity
There are two types of action:
on male or female fertility;
on the foetus (teratogenesis).
9.1 Action on fertility
Chemicals and drugs can act directly on the CNS, particularly the hypothalamus and adenohypophysis, and disrupt libido (impotence), erection and ejaculation, or spermatogenesis by acting on the testicles (atrophy) or producing functional sperm abnormalities (figure 12 ), or acting on DNA and creating genetic and chromosomal aberrations.
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Reproductive toxicity
Genotoxicity. Mutagenesis
Bibliography
Websites
Anses – Nanomaterials
Anses – Endocrine disruptors
CEA – Nanosafe
ECHA – Nanomaterials
...Regulations
Regulation (EC) No 1272/2008 of the European Parliament and of the Council of December 16, 2008 on classification, labeling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006 (see various amendments).
Arrêté du 7 décembre 2009 (JO du 16 décembre 2009, 3 pages): modification des arrêtés du 20 avril 1994 et...
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