Article | REF: BIO6800 V1

Processes of mass cultivation of animal cells

Authors: Annie MARC, Éric OLMOS

Publication date: November 10, 2010, Review date: September 1, 2015

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1. Animal cells for mass culture

1.1 Cell lines

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1.1.1 Normal cells

The first industrial applications of animal cell culture processes date back to the middle of the last century, and involved the production of vaccines. While chicken embryos were still used for some vaccines, alternative cell-based methods quickly became established. Primary cells, derived directly from the digestion of new tissues, retain their differentiation properties close to those of the original organ. However, their cumbersome preparation, limited lifespan, fragility in...

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Animal cells for mass culture