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1. General
1.1 Selection and sizing principles
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The type of bioreactor to be used depends on the number of phases involved in the bioreaction: a single liquid phase, or a gas phase dispersed in a liquid phase (in the case of aerobic cultures), or a solid phase dispersed in a liquid phase (in the case of immobilized enzymes, for example).
It should be noted that, as micro-organisms are smaller than 20 µm in size and have a density very close to that of the culture media, suspensions of micro-organisms in culture media are considered to be a pseudo-homogeneous liquid phase. Of course, this assumption is no longer valid if the micro-organisms tend to agglomerate to form flocs (yeast) or pellets (filamentous fungi).
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Hydrodynamics and transfer performance
Bibliography
References
Theses
- - http://www.sudoc.abes.fr
- MASSÉ (A.) - Contribution à la mise en place d'un réacteur enzymatique à membrane travaillant en milieu supercritique. - Université des sciences et techniques du Languedoc (2001)...
Manufacturers. Suppliers
Non-exhaustive list
Non-exhaustive list of bioreactor builders
Pierre Guérin: http://www.pierreguerin.fr
LSL Biolafitte S.A.: acquired by Pierre Guérin: http://www.pierreguerin.fr
Goavec...
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