8. Systemic toxicity
8.1 Definitions
There are two forms of systemic toxicity:
acute toxicity, the effects of which occur after a single, strong exposure over a short period (a few hours);
-
long-term toxicity (in two forms):
subacute, the effects of which develop progressively with moderate but repeated exposure over a period of days to weeks,
chronic, whose effects develop over the long term following low but repeated exposure over a long exposure period lasting months or years.
Toxicology studies are generally based on a dose/duration relationship. Toxic doses are very high in acute studies, and much lower...
Exclusive to subscribers. 97% yet to be discovered!
You do not have access to this resource.
Click here to request your free trial access!
Already subscribed? Log in!
The Ultimate Scientific and Technical Reference
This article is included in
Laboratory quality and safety procedures
This offer includes:
Knowledge Base
Updated and enriched with articles validated by our scientific committees
Services
A set of exclusive tools to complement the resources
Practical Path
Operational and didactic, to guarantee the acquisition of transversal skills
Doc & Quiz
Interactive articles with quizzes, for constructive reading
Systemic toxicity
Bibliography
Websites
Anses – Nanomaterials
Anses – Endocrine disruptors
CEA – Nanosafe
ECHA – Nanomaterials
...Regulations
Regulation (EC) No 1272/2008 of the European Parliament and of the Council of December 16, 2008 on classification, labeling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006 (see various amendments).
Arrêté du 7 décembre 2009 (JO du 16 décembre 2009, 3 pages): modification des arrêtés du 20 avril 1994 et...
Directory
ATC – Association de toxicochimie
ARET – Association for Research in Toxicology
Exclusive to subscribers. 97% yet to be discovered!
You do not have access to this resource.
Click here to request your free trial access!
Already subscribed? Log in!
The Ultimate Scientific and Technical Reference