13. Glossary
ADME (Absorption – Distribution – Metabolization – Excretion) :
Xenobiotic fate in the body.
Bioavailability; biodisponibility
Form, concentration and lifetime of a xenobiotic in the body.
Clastogenesis; clastogenesis
Chemical or physical action likely to cause breaks or deletions in a DNA molecule, creating a chromosomal aberration.
Concentration létale; lethal concentration
Concentration of a toxic substance that causes the death of a percentage of individuals in a given population, over a given period of time, when exposed to this toxic substance.
Demi-vie ;half life
Time required to eliminate half the amount of xenobiotic in the body.
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Bibliography
Websites
Anses – Nanomaterials
Anses – Endocrine disruptors
CEA – Nanosafe
ECHA – Nanomaterials
...Regulations
Regulation (EC) No 1272/2008 of the European Parliament and of the Council of December 16, 2008 on classification, labeling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006 (see various amendments).
Arrêté du 7 décembre 2009 (JO du 16 décembre 2009, 3 pages): modification des arrêtés du 20 avril 1994 et...
Directory
ATC – Association de toxicochimie
ARET – Association for Research in Toxicology
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