1. Cerebrovascular imaging to better understand the brain

1.1 Areas of use for cerebrovascular imaging

Today, cerebrovascular imaging is used in numerous clinical studies of malformations or dysfunctions of the vascular system, such as arteriovenous malformations, aneurysms, hemorrhages and vascular edema. Vascular parameters accessible by imaging, with or without contrast agents, are :

blood flow ;
the linear velocity of red blood cells

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Cerebrovascular imaging to better understand the brain

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Cerebrovascular imaging devices using two-photon microscopy

Bibliography

(1) - KIM (S.G.) - Perfusion MR imaging : evolution from initial development to functional studies. - Neuroimage, 62(2), p. 672-675 (2012).
(2) - KLEINFELD (D.), MITRA (P.P.), HELMCHEN (F.), DENK (W.) - Fluctuations and stimulus-induced changes in blood...

Software tools

Free software for image processing and analysis:

ImageJ http://rsb.info.nih.gov/ij/

FIJI image http://fiji.sc/Fiji

Websites

http://neurosciences.ujf-grenoble.fr/main-plateformes-4-sub-plate-forme-de-microscopie---microscopie-biphotonique-22-lang-fr.html

http://www.chu-grenoble.fr/doc/Documents/clinatec%20presse%283%29.pdf

...

Events

Spie Photonics West World Congress on (Bio)Photonic Imaging: this congress is held every year on the east coast of America ( http://spie.org/x2584.xml ). The European variant SPIE Photonics Europe http://spie.org/x12290.xml

École thématique Microscopie...

Standards and norms

Laser safety – Part 1: Equipment classification, specifications and user guide - EN 60825-1/A2 -

Regulations

Directive 2010/63/EU of the European Parliament and of the Council of 22 September 2010 on the protection of animals used for scientific purposes.

Arrêté du 1 ^er février 2013 fixant les conditions d'agrément, d'aménagement et de fonctionnement des établissements utilisateurs, éleveurs ou fournisseurs d'animaux utilisés à des fins scientifiques et leurs...