Article | REF: IN405 V1

Phosphine redox catalysis

Authors: Charlotte LORTON, Arnaud VOITURiEZ

Publication date: March 10, 2021

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4. Catalytic Staudinger reaction

4.1 Introduction to the Staudinger reaction

Another major reaction promoted by phosphines is the Staudinger transformation . However, Staudinger reduction must be distinguished from Staudinger ligation (figure 14 ). Both reactions begin with the formation of an iminophosphorane intermediate, starting from an azide (R-N 3 ). This species possessing a P=N double bond was discovered in 1919 by Staudinger and Meyer...

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Catalytic Staudinger reaction