Overview
Français
ABSTRACT
The new generations of biochip systems, the dynamic biochips, allow access to the kinetics of biomolecular interactions and will in the future revolutionize their characterizations. These systems have applications in research and are additionally a routine tool for the identification of molecular signatures. At the moment, the method of choice is based upon surface plasmon resonance imagery techniques. As the use of biochips is easy and reliable, they have become an important tool for the generalized analysis of molecules of small quantities; both in real-time and at low-cost.
Read this article from a comprehensive knowledge base, updated and supplemented with articles reviewed by scientific committees.
Read the articleAUTHORS
-
Pierre LECARUYER: Doctoral student at the Charles Fabry Laboratory of the Optics Institute
-
Michael CANVA: Research Director - Charles Fabry Laboratory of the Optics Institute - Institut d'optique Graduate School, Université Paris Sud, CNRS
INTRODUCTION
A new generation of biochip systems, dynamic biochips provide access to the kinetics of biomolecular interactions (figure 1 ) and should revolutionize their characterization. These systems can be used both in research and as a routine tool for identifying molecular signatures. The method of choice is currently based on surface plasmon resonance imaging techniques.
The Ultimate Scientific and Technical Reference
This article is included in
Bioprocesses and bioproductions
This offer includes:
Knowledge Base
Updated and enriched with articles validated by our scientific committees
Services
A set of exclusive tools to complement the resources
Practical Path
Operational and didactic, to guarantee the acquisition of transversal skills
Doc & Quiz
Interactive articles with quizzes, for constructive reading
Dynamic biochips and imaging in surface plasmon mode
From optical to dynamic biochips
Bibliography
Also in our databaseshttp://www.techniques-ingenieur.fr
Websites to consult
Online catalog http://www.abes.fr/abes/index.html
Theses available online http://tel.archives-ouvertes.fr/
Patent pending
Patent FR n° 05 12 594, "Procédé d'auto-calibration de biopuces" – CNRS (13/12/2005). International extension PCT/EP2006/069683 – (13/12/2006).
Directory
Manufacturers. Suppliers. Distributors (non-exhaustive list)
ACEA Biosciences http://www.aceabio.com/Products/index.htm
Affymetrix http://www.affymetrix.com/index.affx
The Ultimate Scientific and Technical Reference
