1. The benefits of HPLC-ICP-MS coupling for speciation analysis

Analysis of the different chemical forms of a trace element, known as speciation analysis , provides access to an essential dimension of knowledge, and has become increasingly important over the last twenty years. Measuring the total content of an element is no longer sufficient to provide quality information on its reactivity in a given medium, its mobility in the environment or its harmfulness to living organisms. The chemical forms of an element can be very different in nature: they can be different oxidation states, organometallic compounds, complexes or biomolecules (figure

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The benefits of HPLC-ICP-MS coupling for speciation analysis

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Instrumentation

Bibliography

(1) - TEMPLETON (D.M.), FUJISHIRO (H.) - Terminology of elemental speciation – An IUPAC perspective. - Coordination Chemistry Reviews, 352, p. 424-431 (2017).
(2) - SIMON (S.), LOBOS (G.), PANNIER (F.), DE GREGORI (I.), PINOCHET (H.), POTIN-GAUTIER (M.) -...

Standards and norms

Food products – Determining elements and their chemical forms – Determination of inorganic arsenic content in food products of marine and plant origin, by HPLC with anion exchange and inductively coupled plasma mass spectrometry (ICP-MS) - NF EN 16802 - 2016
Water quality – Determination of arsenic chemical forms (III) and (V) – Method using high-performance liquid chromatography (HPLC) with detection by plasma...

Regulations

European Commission Regulation (EC) No 2015/1006 of 25 June 2015 amending Regulation (EC) No 1881/2006 as regards maximum levels for inorganic arsenic in foodstuffs setting maximum levels for certain contaminants in foodstuffs (OJ L. 161, 26/6/2015, p. 14-16)

Directive 2000/53/EC of the European Parliament and of the Council of 27 January 2003 on end-of-life vehicles (OJ L. 269 of 21/10/2000, pp. 34-43)...