8. Benzazepines and benzazocines

The tetrahydrobenzazepine motif is found in a number of cardiovascular drugs and, above all, in a family of active ingredients with anxiolytic activity, the benzodiazepines (figure 14 ). Enlargement of the azepine ring to 8 links provides an interesting compound with analgesic properties, nefopam.

Active ingredient structures with a tetrahydrobenzazepine or hexahydrobenzazocine skeleton — Figure 14...

You do not have access to this resource.

Exclusive to subscribers. 97% yet to be discovered!

You do not have access to this resource.
Click here to request your free trial access!

Already subscribed? Log in!

The Ultimate Scientific and Technical Reference

A Comprehensive Knowledge Base, with over 1,200 authors and 100 scientific advisors

+ More than 10,000 articles and 1,000 how-to sheets, over 800 new or updated articles every year

From design to prototyping, right through to industrialization, the reference for securing the development of your industrial projects

This article is included in

Drugs and pharmaceuticals

This offer includes:

Knowledge Base

Updated and enriched with articles validated by our scientific committees

Services

A set of exclusive tools to complement the resources

Practical Path

Operational and didactic, to guarantee the acquisition of transversal skills

Doc & Quiz

Interactive articles with quizzes, for constructive reading

Subscribe now!

Ongoing reading
Benzazepines and benzazocines

Previous
page Phenylethylamine derivatives

Phenothiazines and their structural analogues

Bibliography

(1) - KINSELLA (G.K.), ROZAS (I.), WATSON (G.W.) - Modelling the interaction of catecholamines with the α1A adrenoceptor towards a ligand-induced receptor structure. - Journal of computer aided molecular design, 19(6), p. 357-367 (2005).
(2) - LIPKIND (G.M.),...