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Research and innovation | REF: IN225 V1

Properties and applications of astatine in nuclear medicine

Author: François GUÉRARD

Publication date: November 10, 2018

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1. Ionizing radiation and cancer therapy

1.1 A reminder of radioactive decay

Radioactivity is a natural physical phenomenon observed in the case of unstable isotopes, known as radionuclides, which leads to their stabilization by the release of a particle and/or an electromagnetic wave from their nucleus. The instability of nuclides appears more frequently as the element's atomic number increases, with all atoms heavier than bismuth (Z > 83) possessing only radioactive isotopes. When it decays, a given radioactive isotope can emit a well-defined particle: either a helium nucleus (α particle), an electron (β particle – ) or a positron (an antielectron noted β + particle). These particles are most often accompanied by electromagnetic...

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