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2. Physical chemistry of pasty systems
The physico-chemical properties of pasty systems are numerous and depend on the intended technical application. Some are common to all pasty systems for pharmaceutical and cosmetic applications, namely rheological properties and the molecular mobility of small molecules incorporated into the pasty matrix, which controls release rate and bioavailability. These properties are controlled by the chemical composition of the product (the formulation) and by the manufacturing process.
2.1 Viscoelasticity
Mechanical or rheological properties are described in simple cases using elastic and viscous moduli. It is more common to speak of mechanical properties in the case of solids and rheology in the case of liquids; but there is no conceptual difference and a unified...
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Physical chemistry of pasty systems
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Bibliography
Bibliography
Standards and norms
European Pharmacopoeia, 10.8, 2022
Websites
European Directorate for the Quality of Medicines & Healthcare http://www.edqm.eu/fr/ (accessed July 14, 2014)
International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH)
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