6. Ointments
Ointments are made up of a single-phase base in which liquid or solid active ingredients are solubilized or dispersed. They can be hydrophobic or hydrophilic, depending on the nature of the base used. There are also water-absorbing ointments, which are in fact emulsions. They are packaged in single- or multi-dose containers.
6.1 Hydrophobic ointments
According to monograph 07/2021:0132, hydrophobic ointments can only absorb small quantities of water. The most commonly used bases for formulating such ointments are solid kerosene, liquid kerosene, light liquid kerosene, vegetable oils, animal fats, synthetic glycerides, waxes and liquid polyalkylsiloxanes. Their hydrophobic nature gives them occlusive properties, forming a barrier on the skin's surface, limiting...
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Ointments
Bibliography
Bibliography
Standards and norms
European Pharmacopoeia, 10.8, 2022
Websites
European Directorate for the Quality of Medicines & Healthcare http://www.edqm.eu/fr/ (accessed July 14, 2014)
International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH)
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