Article | REF: IN404 V1

Artificial Diels-Alderases at the service of green chemistry

Authors: Wadih Ghattas, Jean-Pierre Mahy, Rémy Ricoux, A. Jalila Simaan, Marius Réglier

Publication date: September 10, 2021

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7. Glossary

artificial metalloenzyme

Laboratory-prepared metalloprotein capable of catalyzing a specific chemical reaction.

protein variant

Also called "protein isoform", member of a set of very similar proteins that originate from a single gene or gene family and are the result of genetic differences due to mutations, deletions... While many perform identical or similar biological roles, some isoforms have unique functions.

directed evolution

Biotechnology that mimics natural evolution in an accelerated way in order to modify the properties of a protein by modifying its gene sequence and selecting the desired variants. Directed evolution consists in creating genetic diversity from an initial gene and selecting the best variants for a given property (stability, activity, etc.)....

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