Article | REF: J6008 V1

Biotechnology-based antibiotic production

Authors: Stéphane DELAUNAY, Emmanuel RONDAGS, Pierre GERMAIN

Publication date: September 10, 2003, Review date: September 1, 2016

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1. Different antibiotics and producing micro-organisms

For definitions, please refer to the table at the end of this introduction.

1.1 Antibiotics and secondary metabolites

Secondary metabolites are molecules generally produced by organisms after the active phase of growth, during the phase known as idiophase, as opposed to the active growth phase known as trophophase. The production of secondary metabolites is linked neither to the growth nor to the energy requirements of the producing organisms. The essential differences between primary and secondary metabolites are summarized in table 1 .

We will restrict the definition of antibiotics to all secondary metabolites produced by micro-organisms,...

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Different antibiotics and producing micro-organisms