Article | REF: P1489 V1

Two-dimensional gas chromatography GC-GC and GCxGC

Authors: Xavier FERNANDEZ, Jean-Jacques FILIPPI, Maud JEANVILLE

Publication date: December 10, 2011

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3. GC-GC or heart-cutting two-dimensional gas chromatography

The earliest published GC-GC study describes a valve-based system for connecting the two columns and fractionating the effluent . The valves were metal multiports, which did not avoid the problems associated with metal surface activation, detrimental to the reproducibility of the analyses. In addition, polluted dead volumes and cold trapping effects further reduced efficiency by leading to peak broadening.

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GC-GC or heart-cutting two-dimensional gas chromatography