Article | REF: P1092 V1

Applying NMR to structure determination

Author: Nicole PLATZER

Publication date: September 10, 2002

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1. General information. Available techniques

1.1 Problems to solve

  • Identify the presence of the main types of hydrocarbon groups (aliphatic, ethylenic, aromatic or acetylenic) and functional groups in the compound under examination.

  • Specify the sequence of the various atoms in the skeleton, then determine the location of the functional groups.

  • Identify inter- and intramolecular exchange phenomena.

  • Examine tautomeric forms.

    At this stage, the molecule's planar structure is established.

  • Determine stereochemistry. Two enantiomers give strictly the same NMR...

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General information. Available techniques