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1. Multiscale structure and biological role of collagen
Collagen is the most abundant protein in the human body, and the main component of the extracellular matrix. Collagen fibers give tissues mechanical resistance to stretching.
In biological tissues, cells are surrounded by a complex, bioactive matrix - the extracellular matrix. It provides mechanical support to cells, while regulating their behavior. It is involved in cell survival, proliferation, migration and differentiation. The composition of this matrix varies from one tissue to another, but overall it consists of an interstitial fluid held together by a three-dimensional network of hydrated proteoglycans (polysaccharides attached to a central protein) and fibrous proteins, of which collagen is the most abundant.
Strictly speaking, collagen does not refer to a single protein, but to a family...
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Multiscale structure and biological role of collagen
Natural collagen-based biomaterials
Bibliography
Events
Gordon Research Conferences (GRC), two different themes are addressed at two separate conferences held in the USA every two years (odd-numbered years): collagen on the one hand, and biomaterials and tissue engineering on the other.
https://www.grc.org/find-a-conference/
World Biomaterials Congress (WBC), the next...
Standards and norms
- ISO Évaluation biologique des dispositifs médicaux. Partie 6 : essais concernant les effets locaux après implantation. - NF EN ISO 10993-6 - Avril 2017
Patents
New Hydrogels with Silyl Structure and Production Process. FR 1556628, WO 2017009200 A1.
Directory
Manufacturer – Supplier
Bio-printers and bio-inks (in particular Collagen LifeInk® 200, an ink based on bovine type I collagen)
BioBots, which became Allevi in 2017
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