Article | REF: MED7150 V1

Collagen-based biomaterials for health applications

Authors: Cécile ECHALIER, Ahmad MEHDI, Jean MARTINEZ, Gilles SUBRA

Publication date: May 10, 2018

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2. Natural collagen-based biomaterials

A biomaterial is a "non-living material, used in a medical device and designed to interact with biological systems, whether it is used in a diagnostic device, a tissue or organ substitute, or a functional replacement (or assistance) device" (Chester Consensus Conferences, 1986 and 1991).

A biomaterial is a material designed to replace, repair or support damaged living tissue. Above all, it must be biocompatible with the physiological environment of the subject in which it is implanted, not present a toxicity or infectious risk, induce an immune reaction or have adverse effects on the patient's health. While inert biomaterials do meet these criteria, we prefer bioactive materials that are capable of interacting with cells, participating in their proper functioning, being integrated by the organism and triggering an appropriate...

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Natural collagen-based biomaterials