Article | REF: J8030 V1

Organometallic Flow Chemistry

Authors: Paul KNOCHEL, Niels WEIDMANN, Maximilian GANIEK, Johannes HARENBERG, Benjamin HEINZ, Alexandre DESAINTJEAN

Publication date: June 10, 2019

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2. Continuous flow organometallic reactions

2.1 Continuous flow metallization

Using solutions of TMPMgCl·LICl (16; 1.1 to 1.2 M), in THF tetrahydrofuran, it was possible to metallate numerous pyridines and nitrogenous heterocycles (figure 8 ) .

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