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1. Sequencing methods
DNA, or deoxyribonucleic acid, forms a double-stranded helix. Each strand consists of a sequence of nucleotides, themselves made up of three components: a five-carbon sugar (deoxyribose for DNA and ribose for RNA), a phosphate group and a nitrogenous base: adenine, cytosine, guanine or thymine, often represented by the initials A, C, G and T for DNA, and A, C, G and U (uridine) for RNA. Nucleotide chains are formed by a phosphodiester bond between the OH of the first nucleotide (at C3′ of the deoxyribose) and the phosphate at C5′ of the second nucleotide. Thus, the second nucleotide has an OH available at C3′ to bind to the phosphate of a third nucleotide and so on (figure 1 a ). Synthesis as well as orientation of...
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Sequencing methods
High-throughput sequencing applications
Bibliography
Websites
Biorigami http://www.biorigami.com
France-Génomique https://www.france-genomique.org
GeT platforms http://get.genotoul.fr
Personal Genome...
Events
Annual conference
Annual X-Gen Congress & Expo – San Diego, California http://www.xgencongress.com/
Directories
Manufacturers – Suppliers – Distributors (non-exhaustive list)
23andMe https://www.23andme.com/
454 Life Sciences http://www.454.com/
Celera Genomics https://www.celera.com/
...Statistical and economic data
Sequencing costs per genome
NHGRI Genome Sequencing Program (GSP) data http://www.genome.gov/images/content/cost_per_genome.jpg
Press articles
Ion Torrent PGM Enables Rapid Identification of New Hybrid E. coli Strain in European Outbreak...
The Ultimate Scientific and Technical Reference
