Article | REF: P1420 V1

Solid phase extraction for the analysis of organic compounds

Author: Valérie PICHON

Publication date: December 10, 2006, Review date: January 1, 2023

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2. Coupling mode

This extraction step can be totally dissociated from the chromatographic analysis (off-line preconcentration) or totally integrated into the chromatographic system (on-line preconcentration).

2.1 Delayed extraction

In the off-line method, the adsorbent is contained in a cartridge between two frits, or incorporated into the matrix of a filtration membrane. After conditioning the adsorbent (often with a solvent equivalent to the elution solvent, followed by a passage of pure water), the sample is percolated (figure 1 ). Certain substances retained...

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