Article | REF: P3362 V1

Radionuclides - Application: molecular biology

Authors: François BOURREL, Philippe COURRIÈRE

Publication date: June 10, 2003

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3. Microautoradiography

3.1 Objective

Microautoradiography enables the visualization of silver grains or traces developed in the emulsion by ionizing radiation emitted by the radioligand incorporated into the tissue (receptor localization, radioimmunocytochemistry), using optical and electron microscopy.

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3.2 Principle

The sample can either be mounted on a slide and immersed in a bench containing the liquid autoradiographic emulsion, mounted directly on a slide pre-impregnated with emulsion, or deposited directly on a photosensitive...

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Microautoradiography