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Article | REF: P1455 V1

Liquid chromatography - Separation theory and methods

Authors: Marcel CAUDE, Alain JARDY

Publication date: October 10, 1994

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4. Separation of molecular solutes

4.1 Adsorption chromatography

Adsorption chromatography, also known as liquid-solid chromatography (LSC), uses silica and alumina gels as stationary phases.

It is well suited to the separation of compounds with different polar functional groups (as in the case of many therapeutic molecules) and positional isomers.

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4.1.1 Stationary phases

We will only describe silica gels here, which are the stationary phases most commonly used in CLS.

A silica...

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Separation of molecular solutes
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