Article | REF: K1220 V1

Chemistry without solvents

Authors: Pierrick NUN, Evelina COLACINO, Jean MARTINEZ, Frédéric LAMATY, Max MALACRIA, Jean-Philippe GODDARD, Cyril OLLIVIER

Publication date: November 10, 2008

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5. Conclusion and outlook

The reactions described in this article illustrate the wide range of applications for solvent-free reactions. Processes using a liquid reagent are generally accepted conceptually by chemists. Solid-gas and solid-solid reactions, on the other hand, still encounter resistance. However, the growing number of publications in this field bears witness to a resurgence of activity, with applications in all branches of chemistry.

Although some of these processes are used on a large scale, their effectiveness is not diminished when working on a laboratory scale, and we would like to see them developed and used in these environments, especially as the equipment required is often inexpensive.

Further studies are needed to extend the scope of these reactions, particularly on an industrial scale. Reactions using a liquid reagent are often linked to another...

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Conclusion and outlook