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Article | REF: PHA3064 V1

Herbal supplement Analytical approach

Authors: Xavier FERNANDEZ, Mélissa CLÉMENT CHAMI, Loïc LOFFREDO

Publication date: November 10, 2016

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ABSTRACT

In order to guarantee consumer safety, the French authorities published a new regulatory order in the Official Journal dated June 24th 2014 listing the plants allowed in dietary supplements and how they might be used. This order came into force on January 1st 2015. This article sets out some basic botanical concepts, and makes a comparative study of various analytical frames of reference and tools that stakeholders have at their disposal.

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AUTHORS

  • Xavier FERNANDEZ: Doctor of Science, HDR - University Professor, Université Nice-Sophia Antipolis - Director of the Master 2 Professionnel chimie formulation, analyse et qualité (FOQUAL) - Nice Institute of Chemistry, University of Nice-Sophia Antipolis - UMR CNRS 7272, Nice

  • Mélissa CLÉMENT CHAMI: Doctoral student in science, Université Nice-Sophia Antipolis - Nice Institute of Chemistry, University of Nice-Sophia Antipolis - UMR CNRS 7272, Nice - Chemical engineer, Botanicert, Grasse

  • Loïc LOFFREDO: Technical Manager, Botanicert, Grasse - Master 2 Professionnel chimie formulation, analyse et qualité (FOQUAL), Université Nice-Sophia Antipolis, Nice

 INTRODUCTION

The development of therapeutic chemistry over the last two centuries has led to the development of increasingly sophisticated medicines, often of synthetic origin, and despite a strict regulatory framework, numerous health accidents have occurred. As a result, many consumers have turned their backs on chemical products and turned to natural products. Against this backdrop, a new product has emerged: dietary supplements.

According to decree no. 2006-352 of March 20, 2006, food supplements are defined as follows "Foodstuffs whose purpose is to supplement the normal diet and which constitute a concentrated source of nutrients or other substances with a nutritional or physiological effect, alone or in combination, marketed in dose form, i.e. presentation forms such as capsules, pastilles, tablets, pills and other similar forms, as well as sachets of powder, ampoules of liquid, dropper bottles and other similar forms of liquid or powder preparations intended to be taken in measured units of small quantity". .

With French regulations having been fleshed out with the publication of the Order of June 24, 2014 establishing the list of plants, other than mushrooms, authorized in food supplements and the conditions of their use, manufacturers must now comply with strict quality control.

To ensure that these new requirements do not put professionals involved in the production of food supplements at risk, this article provides an overview of essential botanical concepts, as well as a comparative study of the different standards and analytical tools needed to implement in-depth quality control.

A table of acronyms and a glossary are provided at the end of the article.

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KEYWORDS

analytical chemistry   |   pharmaceutical   |   food industries   |   dietary supplements   |   extraction   |   food supplement

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