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ABSTRACT
This article is devoted to functional enzymology. It briefly describes the main enzymes of viral cell-free structures and of prokaryotic bacterial cells with a primitive level of organization. The role of each enzyme listed is briefly mentioned in order to understand its place in the life and in the multiplication cycle of the entity that produced it. From a therapeutic point of view, this highlights the interest of targeting some of these enzymes in order to stop viral or bacterial infections.
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Read the articleAUTHORS
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Julien Dumond: Doctor of Virology Enzymology - Consultant to pharmaceutical companies, Metz, France
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Serge Kirkiacharian: Doctor of Physical Sciences, Pharmacist - Professor Emeritus of Therapeutic Chemistry, Faculty of Pharmaceutical and Biological Sciences, Université Paris-Sud - Honorary Head of Department, Paris Hospitals, France.
INTRODUCTION
The concepts of biology and biochemistry presented in this article, one of a series devoted to functional enzymology, involve many of the enzymes essential to understanding how living organisms function.
This article describes viral and bacterial enzymes in the context of the functioning of the cell-free and cellular entities that synthesized them.
The International Union of Biochemistry classifies enzymes into seven main families according to the reaction catalyzed and the Enzyme Commission (EC) codes. This simplified classification, presented in article
The subject of this article is the study of the most striking and important enzymes found in acellularia and bacteria, excluding nucleic acid polymerases (EC 2) detailed in the article
At the end of the article, readers will find a glossary and a table of acronyms and notations.
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KEYWORDS
bacteria | virus | enzymes
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Functional enzymology
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