Article | REF: PHA1510 V1

Functional enzymology - Enzymatic classification, genome replication and expression

Authors: Julien DUMOND, Serge KIRKIACHARIAN

Publication date: September 10, 2022

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5. Conclusion

This first part of functional enzymology involved laying the foundations of enzyme classification, so as to be able to begin by characterizing a varied, indispensable category of enzymes found in all living, cell-free organisms: the polymerases involved in genome replication.

The enzymes involved in gene expression were then described in detail:

  • transcription (obtaining messenger RNA from a transcribed strand of DNA),

  • translation (proteosynthesis).

Numerous Nobel Prizes in Chemistry and Medicine have been awarded for work aimed at understanding genome expression and the enzymes involved in this process.

The enzymatic classification established in this article can be consulted for the following three articles

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