Article | REF: NM4050 V1

Mesoporous Silica Nanoparticles (MSN) and biological applications

Authors: Jean-Olivier DURAND, Laurence RAEHM

Publication date: July 10, 2009

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1. Summary

Jean-Olivier DURAND is a 1 re research fellow at CNRS-Montpellier. Laurence RAEHM is a lecturer at Montpellier 2 University.

The oldest method for synthesizing mesoporous silicas involves the sol-gel process in a basic medium (figure 1 ), by polycondensation hydrolysis of a silica precursor (most often tetraethoxysilane) in the presence of a surfactant. The surfactant is of the cationic type (CTAB), which structures the silica formation by ionic interactions between negatively charged silicates and positively charged ammonium, with the formation of supramolecular assemblies.

CTAB: cetyltrimethylammonium bromide

Micellization...

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