2. Culture media
Over the past 50 years, the composition of culture media has evolved considerably. Whereas the very first media used only biological fluids, it very quickly became necessary to offer better-controlled formulations based on compounds essential for cell growth. There are two main categories of culture media, depending on whether or not they contain animal serums. The use of serum-free media is becoming the norm for most processes under development or recently introduced. On the other hand, some processes still use serum because of their long-standing validation, the use of more demanding cells, or the diagnostic use of the products generated.
2.1 Culture media with animal serum
Serum-containing culture media, developed around the middle of the last century,...
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Impact of environmental parameters on cell kinetics
Bibliography
Websites
LEEM study. Bioproduction in 2008: state of play and recommendations for French attractiveness. http://www.leem.org/dossier/101/etude-bioproduction-en-2008-etat-des-lieux-et-recommandations-pour-l-attractivite-1297.htm
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ESACT Congress, held every two years in Europe http://www.esact.org/meetings_esact.html
Congress of the engineering foundation: cell culture engineering, held every two years, mainly in the U.S.
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ESACT Association: European Society of Animal Cell Technology http://www.esact.org/
Association ACTIP: Animal Cell Technology Industrial Platform http://www.actip.org/
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