Article | REF: J2310 V1

Lipid nanocarriers as drug delivery systems

Authors: Anne-Claude COUFFIN, Thomas DELMAS

Publication date: March 10, 2013

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2. Lipid systems developed for research and clinical use

2.1 Liposomes

Pioneers of lipid systems, liposomes were first formulated by Bangham in 1964 as characterization tools in the study of biological membrane dynamics . The concept of using these vesicles as cell delivery systems is based on the possibility of fusion between these vectors and the targeted cell membranes.

In its simplest form, a liposome is a vesicle with an aqueous core, whose membrane, in the form of...

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Lipid systems developed for research and clinical use