2. Bone autograft
Fracture failure may have mechanical or biological origins and often results in the formation of a mixture of fibrous and osseous tissues, preventing the restoration of bone continuity. What's more, therapeutic advances in orthopedics often undermine bone's natural ability to repair itself. Indeed, the treatment of tumors, cysts or infectious foci often requires the removal of bone pieces too large for the natural self-repair process alone to induce bone consolidation.
Since the beginning of the twentieth century, bone grafting has been described as the benchmark technique for promoting fracture healing or filling lost bone substance. Worldwide, more than 2.2 million...
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Bone autograft
Bibliography
Websites
Haute Autorité de Santé for the evaluation of bone substitutes http://www.has-sante.fr/portail/upload/docs/application/pdf/2013.06/rapport_devaluation_des_substituts_osseux.pdf
Events
European Society for Biomaterials http://www.esbiomaterials.eu/
French Society of Orthopaedic and Traumatological Surgery http://www.sofcot.fr/
Standards and norms
- Norme sur l'évaluation biologique des dispositifs médicaux - NF EN ISO 10993-1 -
Regulations
Article L. 1243-2 of the French Public Health Code: "The preparation, preservation, distribution and transfer, for autologous or allogeneic therapeutic purposes, of tissues and their derivatives and cell therapy preparations may be carried out by establishments and organizations authorized for this purpose, after consultation with the Agence de la biomédecine, by the Agence nationale de sécurité du médicament et des produits...
Directory
Laboratories – Design offices – Schools – Research centers (non-exhaustive list)
École des mines de Saint-Étienne http://www.ism.univmed.fr
Institute of Movement Sciences http://www.ism.univmed.fr
Osteoarticular Bioengineering...
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