Article | REF: MED7200 V1

Biomaterials for tissue engineering: perspectives for bone repair

Authors: Mickael DESCHEPPER, Joseph PAQUET, Adrien MOYA, Mathieu MANASSERO, Morad BENSIDHOUM, Hervé PETITE

Publication date: April 10, 2015

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2. Bone autograft

Fracture failure may have mechanical or biological origins and often results in the formation of a mixture of fibrous and osseous tissues, preventing the restoration of bone continuity. What's more, therapeutic advances in orthopedics often undermine bone's natural ability to repair itself. Indeed, the treatment of tumors, cysts or infectious foci often requires the removal of bone pieces too large for the natural self-repair process alone to induce bone consolidation.

Since the beginning of the twentieth century, bone grafting has been described as the benchmark technique for promoting fracture healing or filling lost bone substance. Worldwide, more than 2.2 million...

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Bone autograft
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