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2. Formulation
Toothpaste comes in several forms: paste, gel, paste-gel combination, liquid or powder. Only the first two forms, which are the most commonly used, are detailed here.
2.1 Paste
Figure 11 summarizes the various phases of a paste formulation. Generally speaking, a toothpaste in paste form is a suspension, i.e. a dispersion of fine solid particles in a liquid in which they are insoluble. This mixture is therefore a heterogeneous system consisting of a continuous outer liquid phase, called the dispersing phase, and an inner phase of fine solid particles, called the dispersed phase. The addition of a stabilizer (e.g. a gelling agent) stabilizes the medium over time
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Bibliography
Websites
National Agency for the Safety of Medicines and Health Products http://ansm.sante.fr/
BAILLY (M.), Dental products back on the market http://www.lsa-conso.fr
French Union for Oral Health http://www.ufsbd.fr/
...Events
Perfumes and Cosmetics Congress – Regulatory issues, held every year in Paris http://www.congres-parfumscosmetiques.com/fr/
Cosmetagora tradeshow, held every year in Paris http://www.cosmetagora.fr/
Salon Beyond Beauty,...
Standards and norms
- Oral medicine – Toothpastes – Requirements, test methods and marking - ISO/DIS 11609 -
Regulations
Regulation (EC) No 1223/2009 of the European Parliament and of the Council of 30 Nov. 2009 on cosmetic products, OJ L 342, 22 Dec. 2009, p. 59-209.
Commission Regulation (EU) No. 655/2013 of July 10, 2013 laying down common criteria that cosmetic claims must meet in order to be used, OJ L 190, July 11, 2013, pp. 31-34.
Patents
Stripe toothpaste, color-stable, WO 1998020849 A1.
Toothpaste made from coloured silica, WO 2005046631 A1.
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