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4. Extract characterization and identification of active compounds
4.1 Toxicity assessment
Before committing substantial financial resources to the development of an active ingredient from a target plant, it is crucial to assess the extract's toxicity. This stage can be carried out at various stages of development. Integrating this criterion at an early stage enables us to distinguish between plants and eliminate those presenting an obvious toxicological risk at an early stage. However, not all tests are suitable for screening, making them costly and time-consuming to carry out at this stage, leading some laboratories to postpone this step.
The assessment of the toxicity of ingredients and finished products is regulated differently around the world. In China, although animal testing is no longer compulsory, it is not prohibited...
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Extract characterization and identification of active compounds
From plant to ingredient
Bibliography
Standards and norms
- Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products – Part 1: Ingredient definitions. - ISO 16128-1 - 2016
- Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products – Part 2: Criteria for ingredients and products. - ISO 16128-2 - 2017
- Cosmetics – Good Manufacturing Practices (GMP) – Guidelines for good...
Regulations
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European cosmetics regulations: https://eur-lex.europa.eu/ (page consulted on January 6, 2024)
Regulation (EC) No 1223/2009 of the European Parliament and of the Council of November 30, 2009 on cosmetic products (2009).
Regulation (EU) No 511/2014 of the European...
Directory
Manufacturers – Suppliers – Distributors (non-exhaustive list)
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Suppliers of cosmetic active ingredients (non-exhaustive list)
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