4. Lipid nanovectors as nanomedicines

4.1 Interactions with biological media: nanotoxicity

For several years now, the chemical industry and its technological advances have made available to formulators a multitude of ingredients of varying degrees of purity, and in significant quantities. In just a few years, the range of lipids derived from the refining of oils of various origins has tripled. However, they must be chosen rationally, based on their physicochemical properties and safety (non-toxicity), in order to be used as excipients in the composition of nanomedicines. The list entitled Inactive Ingredients Guide (IIG) drawn up by the Food and Drug Administration (FDA) –, indicating materials already tested, their quantity and the route of administration for which they are approved –, is a valuable aid in this choice....

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Lipid nanovectors as nanomedicines

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page Designing lipid nanoemulsions

Applications in the medical sector

Bibliography

(1) - MOSS (G.), SMITH (P.), TAVERNIER (D.) - Glossary of class names of organic compounds and reactive intermediates based on structure. - In IUPAC Recommendations 1994, I.U.o.P.a.A. Chemistry, Editor (1994).
(2) - ROSSI (J.), LEROUX (J.C.) - Principles in...

Digital media

CNRS sagascience: vectorization file http://www.cnrs.fr/cw/dossiers/dosnano/decouv/vecto/vecto.htm

Websites

NANOSAFE: use and production of nanomaterials http://www.nanosafe.org

Events

World Congress on Emulsion. International trade fair on fundamental and applied aspects of emulsions, held every 4 years at the Palais des Congrès in Lyon, France. http://www.cme-emulsion.com

PharmSciFair. International trade fair on fundamental and applied aspects of pharmaceutical sciences, held every 2 years in a European city....

Standards and norms

European Technological Platform for Nanomedecine, Nanotechnology for Health: Vision paper and basis for a strategic research agenda for nanomedecine, ETPN, 2005, European Commission Publication Office, Brussels

Cancer Nanotechnology Plan: a strategic initiative to transform clinical oncology and basic research through the direct application of nanotechnology, NIOH, National Cancer Institute,...

Regulations

Agence Nationale de Sécurité du Médicament et des Produits de Santé ANSM: an agency whose mission is to guarantee the safety of healthcare products throughout their life cycle. It issues marketing authorizations for drugs (AMM) and clinical trial authorizations. http://ansm.sante.fr

US Food and Drug Administration: federal agency regulating...