5. Applications in the medical sector
A few applications illustrate the potential of lipid nanovectors as nanomedicines.
5.1 Topical and transdermal applications
As in the case of liposomes, the cosmetics industry has brought the use of lipid nanospheres, and more specifically SLNs, to the attention of the general public. Their compositions, based on biocompatible, biodegradable lipids and triglycerides derived from biocompatible oils or waxes, ensure that these objects are very well tolerated by the skin. Incorporated into or in the form of creams (oil in water) and in the absence of active ingredients, these lipid nanoparticles can firstly form an occlusive film on the surface of epidermis, thus limiting skin dehydration while ensuring lipid regeneration
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Applications in the medical sector
Bibliography
Digital media
CNRS sagascience: vectorization file http://www.cnrs.fr/cw/dossiers/dosnano/decouv/vecto/vecto.htm
Websites
NANOSAFE: use and production of nanomaterials http://www.nanosafe.org
Events
World Congress on Emulsion. International trade fair on fundamental and applied aspects of emulsions, held every 4 years at the Palais des Congrès in Lyon, France. http://www.cme-emulsion.com
PharmSciFair. International trade fair on fundamental and applied aspects of pharmaceutical sciences, held every 2 years in a European city....
Standards and norms
European Technological Platform for Nanomedecine, Nanotechnology for Health: Vision paper and basis for a strategic research agenda for nanomedecine, ETPN, 2005, European Commission Publication Office, Brussels
Cancer Nanotechnology Plan: a strategic initiative to transform clinical oncology and basic research through the direct application of nanotechnology, NIOH, National Cancer Institute,...
Regulations
Agence Nationale de Sécurité du Médicament et des Produits de Santé ANSM: an agency whose mission is to guarantee the safety of healthcare products throughout their life cycle. It issues marketing authorizations for drugs (AMM) and clinical trial authorizations. http://ansm.sante.fr
US Food and Drug Administration: federal agency regulating...
Patents
Recent advances and patents on Solid Lipid nanoparticles. in Recent patent on drug delivery and formulation, 2008, 2, 120-135
Process for producing nano-emulsions. WO/2008/104717
Encapsulation of lipophilic or amphiphilic therapeutic agents in nanoemulsions. WO/2010/018223
Lipid nanocapsules, preparation method and use as medicine. WO/2001/064328...
Directory
Manufacturers – Suppliers – Distributors (non-exhaustive list)
GEA Niro Soavi, suppliers of high-pressure homogenizers http://www.nirosoavi.com
Microfluidics Corporation, suppliers of microfluidic homogenizers http://www.microfluidicscorp.com
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