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3. Conclusion
One of the major challenges facing the chemical, pharmaceutical and cosmetics industries in the 21st century is to replace synthetic and petroleum-based derivatives with new renewable, non-toxic, biodegradable raw materials derived from agro-resources. Today's pharmaceutical industry is therefore in great demand for biosourced excipients, which must be at least as functional as, if not superior to, petrochemical or synthetic derivatives, without being harmful from an environmental point of view. But these new excipients must also be able to meet the demands for innovation that go hand in hand with technological advances (eco-responsible chemistry, sustainable processes) and medical advances (nanomedicine, development of mucosal pathways...). As demonstrated in this article, plant lipids and proteins offer a wide range of properties that can be used to create excipients with multiple biopharmaceutical...
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Conclusion
Glossary
Bibliography
Regulations
European Pharmacopoeia 9th edition 9.8, 2019.
Handbook of pharmaceutical Excipients, 8 e edition, 2017. Published by Pharmaceutical Press and The American Pharmacists Association. Edited by P.J. Sheskey, W.G. Cook and C.G. Cable.
Patents (non-exhaustive list)
Lipid-based nanocarrier systems for using cancer treatment. GURSOY (R.N.), CEVIK (O.). European patent EP2790683 (2016).
Process for making protein delivery matrix and uses thereof. PAQUIN (P.), SUBIRADE (M.), BEAULIEU (L.). AU2002245979 (2002).
Modified protein excipient for delayed-release tablet. CAILLARD (R.), LECLERC (P.-L.), SUBIRADE (M.). US2011076326...
Directory
Suppliers – Distributors (non-exhaustive list)
Abitec, 501 W 1st Ave, Columbus, OH 43215, USA. Supplier of lipid-based pharmaceutical excipients.
BASF France SAS – Industrie et Service, 49, avenue Georges Pompidou, Levallois 92593. Production of specialty chemicals for most industries....
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