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1. Laboratory-tested efficacy
Tests of active ingredient efficacy and penetration can be carried out on operative waste, in which case they are referred to as "ex vivo" tests, or on in vitro cell culture models, which are as close as possible to real-life conditions: models of stressed, functionalized, two- or three-dimensional skin.... The role of cell and tissue engineering in cosmetology is crucial for understanding physiological and pathological mechanisms, and proposing innovative therapies.
1.1 Regulatory framework
Constraints on tests carried out on human cells in laboratories concern the recovery of surgical waste: such waste comes from surgical procedures and can be stored in "biobanks", or used directly...
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Laboratory-tested efficacy
Clinical objectivation of cosmetic efficacy
Bibliography
Websites
Center d'Études et de Recherche sur le Tégument : http://www.cert-besancon.com
Patents
Device for measuring isometric forces in organic tissue by capacitive method. December 19, 2001, n° 01 16485.
Hanging device for biological tissue. December 19, 2001, n° 0116485.
Method and device for quantifying the penetration of molecules or substances into or through protective membranes. 07 August 2007, FR07 57289.
Diffusion insert for membrane analysis,...
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Organizations – Federations – Associations (non-exhaustive list)
International Society for Biophysics and imaging of the Skin: http://www.i-s-b-s.org
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