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7. Conclusion
Centrifugal partition chromatography is a technology in the liquid chromatography family, but without a solid support. Its mode of operation offers a wide choice of liquid phases, providing complementary solutions to supported chromatography, particularly for fragile, poorly soluble molecules... While the technology is already well known for fractionating natural extracts on a preparative scale, its change of scale means that it can now be used for applications in biotechnology and industrial purification.
The development of a CPC purification method is therefore based on :
the choice of phases with considerations similar to those for liquid-liquid extraction;
characterization of hydrodynamics and material transfer (with or without reaction);
modeling...
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Unit operations. Chemical reaction engineering
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Conclusion
Glossary
Bibliography
Events
CCC (CounterCurrent Chromatography) International Congress, held every two years
Patents
FR 2 920 674 (A1) – Cells and binding channels for centrifugal partition chromatography (2009)
FR 2 953 144 (A1) – Device and method for bringing immiscible fluid phases into contact by centrifugal force (2009)
FR 2 908 054 (A1) – CPC-type liquid-liquid separation process and system for eliminating cavitations (2008)
FR 2 923 398 (A1) – Centrifugal partition...
Directory
Manufacturers – Suppliers – Distributors (non-exhaustive list)
Everseiko Corporation (Japan) http://www.everseiko.co.jp/scientific/hpcpc.html
Gilson – Armen Instruments (France) http://www.armen-instrument.com/
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