Article | REF: NM4025 V1

Multifunctional gold nanoparticles for imaging and therapy

Authors: Gautier LAURENT, Gloria JIMENEZ SANCHEZ, Rana BAZZI, François LUX, Pascal PERRIAT, Olivier TILLEMENT, Stéphane ROUX

Publication date: December 10, 2014

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2. Nanoparticles against cancer?

The treatment of cancerous tumors is a real public health issue, and for many years now, the scientific community has been working on themes involving disciplines as diverse as medicine (oncology), cell biology, chemistry, pharmacy (galenics, vectorization and targeting) and even particle physics, in particular radiation-matter interactions... Various approaches and strategies have been explored. While significant advances have been made in some forms of cancer, others have resisted the therapeutic arsenal developed to date (surgery, chemotherapy and/or radiotherapy). The case of glioblastoma (the most common brain tumour) is emblematic, as the survival of patients currently treated is no better than that observed thirty years ago. Successful treatment requires total and exclusive eradication of the tumour. Eradication must be total, because the presence of a few residual cancer cells is...

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Nanoparticles against cancer?