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4. Conclusion
Supramolecular chemistry is a fascinating field at the interface of many disciplines. The 1987 Nobel Prize, awarded jointly to J.M. Lehn, D.J. Cram and C.J. Pedersen, celebrated the first steps of an emerging discipline that was to see spectacular developments in organic synthesis, biology, physics and materials science. The first source of inspiration was the living. The aim was to understand, reproduce and exploit selective recognition processes involving molecules and/or macromolecules of biological origin. This seminal work, celebrated by the highest scientific distinction of our time, has enabled us to better define the perimeter of this burgeoning field as that of chemistry "beyond the molecule", involving so-called "weak" non-covalent bonds, as opposed to the high-energy covalent bonds classically used in organic synthesis to build molecules step by step from atoms.
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Conclusion
Glossary
Bibliography
Software tools
Visualization of complex molecular structures (proteins, polynucleotides): the NGL Viewer :
AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. Web-based molecular graphics for large complexes. Bioinformatics: bty 419, 2018.doi :10.1093bioinformatics/bty 419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res...
Websites
Theoretical and Computational Biophysics Group at the University of Illinois at Urbana-Champaign (USA):
How enzymes work:
https://pdb101.rcsb.org/learn/videos/how-enzymes-work
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Events
Symposium: International Symposium on Macrocyclic and Supramolecular Chemistry (ISMSC), held annually.
International Conference on Calixarenes, is held every two years.
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