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2. Plant proteins and their potential for green excipients
2.1 Main protein sources and their current use
Proteins are natural nitrogenous polymers ranging in size from several thousand to several million daltons. Made up of one or more peptide chains, their unit is the amino acid. All amino acids share a common structure, consisting of a carboxylic acid function, a primary amine and a side chain. The latter presents a wide variety of chemical structures, giving proteins their particular properties. The amino acid sequence has its own three-dimensional organization (or folding). From sequence to folding and association, there are four levels of protein structural organization:
the primary structure, defined by the linear sequence of amino acids linked by peptide bonds;
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Plant proteins and their potential for green excipients
Conclusion
Bibliography
Regulations
European Pharmacopoeia 9th edition 9.8, 2019.
Handbook of pharmaceutical Excipients, 8 e edition, 2017. Published by Pharmaceutical Press and The American Pharmacists Association. Edited by P.J. Sheskey, W.G. Cook and C.G. Cable.
Patents (non-exhaustive list)
Lipid-based nanocarrier systems for using cancer treatment. GURSOY (R.N.), CEVIK (O.). European patent EP2790683 (2016).
Process for making protein delivery matrix and uses thereof. PAQUIN (P.), SUBIRADE (M.), BEAULIEU (L.). AU2002245979 (2002).
Modified protein excipient for delayed-release tablet. CAILLARD (R.), LECLERC (P.-L.), SUBIRADE (M.). US2011076326...
Directory
Suppliers – Distributors (non-exhaustive list)
Abitec, 501 W 1st Ave, Columbus, OH 43215, USA. Supplier of lipid-based pharmaceutical excipients.
BASF France SAS – Industrie et Service, 49, avenue Georges Pompidou, Levallois 92593. Production of specialty chemicals for most industries....
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