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1. The essential consequences of polymorphism in the pharmaceutical field
Previous articles and have already given a glimpse of the main consequences expected in the pharmaceutical sector.
They mainly concern :
dissolution kinetics and, possibly, bioavailability;
the manufacturability of the active ingredient and the finished product;
the stability of the latter two.
These areas have already been more or less developed, so we'll confine ourselves here to briefly touching on certain aspects.
1.1 Polymorphism / dissolution kinetics and bioavailability
Most drugs are still prescribed orally (tablets, capsules, suspensions,...
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The essential consequences of polymorphism in the pharmaceutical field
References
Recent theses
- - http://www.sudoc-abes.fr
- LULLO (E.) - Le polymorphisme et le pseudopolymorphisme de l'état solide : conséquences sur la cinétique de dissolution de certaines formes orales solides. - Université Louis-Pasteur...
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The Ultimate Scientific and Technical Reference