Article | REF: MED4050 V1

Biomedical field and the Big data issues

Author: Pierre-Antoine GOURRAUD

Publication date: June 10, 2021

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ABSTRACT

This article discusses the quantitative leap forward in accessing large amount of data in the specific context of biomedical practices,”.  The specificities of biomedical data in are questioned using a 5-letter mnemonic: V, N, C, P, T. "V" for Variability, "N" for large and small Numbers, "C" for ever-changing diagnostic Categories, "P" for the profoundly Probabilistic nature health outcomes, and "T" for their lasting nature of risk exposure and treatments over time. These characteristics of health data are as many challenges for the future of a medicine that becomes more "4P": a medicine that is more predictive, more personalized, more preventive and more participatory.

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AUTHOR

  • Pierre-Antoine GOURRAUD: University Professor Hospital Practitioner - Nantes University, CHU, INSERM,Centre de Recherche en Transplantation et Immunologie, UMR 1064, ATIP-Avenir , Nantes, France - CHU de Nantes, INSERM, CIC 1413, Pôle Hospitalo-Universitaire 11 : Santé Publique, Clinique des données, Nantes, France

 INTRODUCTION

The arrival of "big data" in healthcare coincides with the emergence of so-called "precision" medicine , i.e. medicine where the aim is to take better account of patients in terms of both their overall pathology and their individual characteristics. The French National Authority for Health (HAS) refers to this as the 5B rule , i.e. "administer the right medicine, at the right dose, on the right route, at the right time, to the right patient". One of the driving forces behind precision medicine is the dual ease of access to objective data and on-the-fly calculation that is characteristic of "big data". The digitization of health data, which is becoming an increasingly important part of patient care and treatment, is making it more and more feasible. Nevertheless, if the medical field, like others before it, is set to be transformed by on-demand calculations based on data that has become more accessible because it has been digitized, we need to question the very substratum of a real or supposed Big Data revolution. Indeed, it is first and foremost the nature of the data to which we now have massive access (big data) that contains the uses, hopes and limits of the emergence of new medicine in the big data era. This article highlights five characteristics of health data to help us understand the challenges of Big Data in healthcare, and to make a wide range of applications possible in this field.

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Healthcare and the challenges of big data