Article | REF: P1476 V1

Planar chromatography: applications

Authors: Dominique PRADEAU, Chantal DAUPHIN

Publication date: March 10, 2002

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5. Pharmaceutical products

In the pharmaceutical industry, thin layer chromatography is used in the quality control laboratory to analyze raw materials and finished products.

This method naturally meets the objective of reducing control costs, as it is easy to implement and requires much lower solvent volumes than liquid chromatography, while retaining analytical characteristics close to those of the latter.

In order to take full advantage of this technique's performance, particularly in the field of quantification, it is necessary to invest in suitable equipment: the automatic depositor is essential for deposit reproducibility, the densitometer scanner for result quantification, and video-documentation for archiving (quality assurance). Over and above the purchase of such equipment, the motivation of technicians is an essential asset, as it has to be admitted that...

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