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5. Tandem mass spectrometry, MS-MS or MSn
5.1 General description
The principle of tandem-mode mass spectrometry or MS-MS is shown in figure 19 . It involves gradually :
select an ion according to its m/z ratio, which is generally present in the ionization source among other charged species;
specifically induce its fragmentation by physical activation processes;
record the mass spectrum of the ions produced when its molecular structure breaks up.
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Tandem mass spectrometry, MS-MS or MSn
Conclusion
Bibliography
Software tools
Molecular Weight Calculator, Version 6.50 by Matthew Monroe. Program distributed free of charge via download http://www.alchemistmatt.com/http://ncrr.pnl.gov/software/http://come.to/alchemistmatt
...Websites
NIST Chemistry WebBook. NIST standard reference database http://webbook.nist.gov/chemistry/
Main mass spectrometer manufacturers http://www.sisweb.com
Free documentary resource with a section dedicated to mass spectrometry
The Ultimate Scientific and Technical Reference
