Article | REF: K1260 V2

Supported Chemistry on Solid Phase

Author: Géraldine GOUHIER

Publication date: September 10, 2018

You do not have access to this resource.
Click here to request your free trial access!

Already subscribed? Log in!


Français

6. Solid-phase synthesis: application examples

Since the early 1990s, the popularity of supported chemistry has been applied to combinatorial techniques in pharmaceutical and agrochemical research for molecular recognition, catalysis and the construction of new molecules. A large number of organic chemistry reactions have been successfully transposed to solid-phase synthesis. Numerous journals describe the various uses of polymers and their applications in synthesis (see the documentation section of this article). A few selected examples are given here to illustrate the use of supported reagents, auxiliaries and chiral catalysts.

6.1 Supported reagents

The Mitsunobu reaction was, like many others, applied to the solid phase. Triphenylphosphine is then supported on polystyrene, thus avoiding the delicate...

You do not have access to this resource.

Exclusive to subscribers. 97% yet to be discovered!

You do not have access to this resource.
Click here to request your free trial access!

Already subscribed? Log in!


The Ultimate Scientific and Technical Reference

A Comprehensive Knowledge Base, with over 1,200 authors and 100 scientific advisors
+ More than 10,000 articles and 1,000 how-to sheets, over 800 new or updated articles every year
From design to prototyping, right through to industrialization, the reference for securing the development of your industrial projects

This article is included in

Drugs and pharmaceuticals

This offer includes:

Knowledge Base

Updated and enriched with articles validated by our scientific committees

Services

A set of exclusive tools to complement the resources

Practical Path

Operational and didactic, to guarantee the acquisition of transversal skills

Doc & Quiz

Interactive articles with quizzes, for constructive reading

Subscribe now!

Ongoing reading
Solid-phase synthesis: application examples
Outline