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4. Galenic formulation
In this section, we describe the use of microfluidic supports to obtain finished pharmaceutical products. These end products are innovative pharmaceutical formulations such as i) "soft phases" (e.g. liposomes or other lipid nanoparticles, micelles, vesicles, etc.), ii) solid particles (e.g. lipid particles or polymeric capsules), iii) or three-dimensional matrix networks called "microgels"
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Galenic formulation
The benefits of organ-on-chip
Bibliography
Standards and norms
- Microfluidic devices – Interoperability requirements concerning dimensions, connections and initial classification of devices - ISO 22916 - 2022
- Automated liquid handling systems – Part 1: Vocabulary and general requirements - ISO 23783-1 - 2022
- Microfluidics – Vocabulary - ISO 10991 - 2023
- Automated liquid handling systems – Uncertainty of measurement procedures - ISO/TR 6037 - 2024
Regulations
Commission Directive (EU) 2017/1572 of September 15, 2017 supplementing Directive 2001/83/EC of the European Parliament and of the Council as regards principles and guidelines of good manufacturing practice for medicinal products for human use (CELEX: 32017L1572)
Directory
European EMPIR project "Establishing metrology standards in microfluidic devices" (MFMET, 20NRM02): https://mfmet.eu
GDR Micro and Nanofluidics : https://www.gdrmicrofluidique.com
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