Article | REF: P3280 V1

Medicinal chemistry - Structure and activity of medicinal products

Author: Serge KIRKIACHARIAN

Publication date: December 10, 2007, Review date: August 1, 2023

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9. Physico-chemical changes in a drug

Nota

drug stability is linked to the reactivity of functional groups, and to chemical reactions and interactions of molecules with excipients and additives used in the preparation of galenic forms. This subject is developed in the article Réactivité des groupements fonctionnels (Techniques de l'Ingénieur, traité Analyse et Caractérisation) [66].

Water-soluble dexamethasone salts
Figure 49  -...
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Physico-chemical changes in a drug