Article | REF: P1494 V1

Main evolutions in liquid chromatography

Author: Davy GUILLARME

Publication date: June 10, 2014, Review date: November 15, 2023

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2. Alternative strategies to RPLC

2.1 HILIC mode

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2.1.1 Principle

The term "hydrophilic interaction chromatography" HILIC was defined in 1990 to describe an alternative strategy to normal phase polarity chromatography NPLC, enabling the retention...

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Alternative strategies to RPLC